| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Thymogam | Bharat Serums and vaccines Ltd. | Nairobi Enterprises Limited | 250mg | 5ml | Injection | KES 8,000 |
| Anti-thymocyte globulin More info | |
|---|---|
| Mode Of Action | For anti-D the mechanism of inhibition of antibody synthesis is unclear, but rapid destruction and clearance of Rh-positive cells from the circulation seem to play a role. |
| Drug Indication | Prevention and treatment of organ transportation rejection. |
| Precautions | Since it causes immunosuppression extra precutions need to be taken when used with other immunosupprants; neutropenia; anaemia; thrombocytopenia |
| Contra-Indications | Allergic reactions against the antibody animal source; fluid overload |
| Side Effects | Neutropenia; anaemia; thrombocytopenia; opportunistic infection; myalgia; rash; thrombophlebitis; cytokine release syndrome; serum sickness; anaphylaxis |
| Dosage | Maximum dose: adult-IV 30mg/kg daily; child - 25mg/kg daily |
| Pregnancy Category | Category B3 |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals show evidence of an increased occurrence of foetal damage, the significance of which is uncertain in human |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Sera & Immunoglobulins |